WinRAR x64 (64 bit) v5.40 + KeyReg [ChattChitto RG].exe
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WinRAR X64 (64 Bit) V5.40 KeyReg [ChattChitto RG]
Movies, Games, Music, Apps, Books.Maternal pre-pregnancy vitamin D status and risk of autism spectrum disorders: A systematic review and meta-analysis.
Maternal vitamin D status during pregnancy may potentially affect the risk of autism spectrum disorders (ASDs). We conducted a comprehensive literature search, including meta-analysis and subgroup analysis to summarize the available evidence on the association between maternal vitamin D status and risk of ASD. We identified a total of 21 case-control studies with 56,964 participants. The pooled summary odds ratio (OR) for ASD in vitamin D deficient mothers versus non-deficient mothers was 2.27 (95% confidence interval (CI): 1.91-2.71; I(2)=46.7%). The subgroup meta-analyses showed significant associations of maternal vitamin D deficiency with ASD risk in all subgroup analyses. Stratified analysis by low-risk of bias study showed a reduced association of vitamin D deficiency with ASD in high-risk of bias studies (OR=2.50; 95% CI: 1.58-3.97; I(2)=0%). Our meta-analysis suggests that maternal vitamin D deficiency during pregnancy is a risk factor of ASD.
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